U.S. Census of 1850 has Hamilton (30) and Elizabeth (35) Rutherford living in House 1517, Ward 5 of St Louis, Missouri. Both were born in Ireland. Edward Rutledge, 20, is living with them.
To show that this Edward is indeed a relative in question, the Bellefontaine Cemetery has these Rutherfords buried in the Rutledge family plot, Lot 16.
Record via FamilySearch,
accessed 1 Dec 2015.
abt. 1850